Integrated Cannabis Company, Inc.

(CSE:ICAN.CN) (OTCQB:ICNAF)

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Integrated Cannabis Company, Inc. Announces Positive Results from Clinical Study of X-SPRAYS Sleep Product

VANCOUVER, BRITISH COLUMBIA – October 4, 2018 – Integrated Cannabis Company, Inc. (CSE: ICAN, OTCQB: ICNAF) (“Integrated Cannabis”), is pleased to announce the successful completion and positive results of a controlled trial of its proprietary Sleep product.

 

The controlled 60 patient trial was completed with a renowned pain clinic in Southern California and the results were highly favorable; resulting in improvement in patients’ sleep patterns combined with the unexpected, but highly desirable, decrease in the level of pain.  The study results have been published in the peer reviewed journal: International Journal of Pharmacy and Life Sciences (Int. J. of Pharm. Life Sci., Vol. 9:5722-5729).

 

“The unique formulation of ingredients in the X-SPRAYS™ sleep supplement contributed to a significant improvement in sleep quality together with a reduction in daytime sleepiness, pain, and depression, when compared to the control group. The study was conducted in a controlled and regulated clinical environment, which prohibits the test of cannabis products. Therefore the study was on our non-cannabinoid product. However, our experience with the infusion of CBD into the tested formulation has rendered profound increased benefits. Furthermore, we are actively seeking clinical study relationships in legal jurisdictions outside of North America for our cannabinoid-based products and expect to replicate the aforementioned study in the near term. The spray has the added benefit of being easy to use, is fast acting, promotes a superb night’s rest and does not leave you feeling groggy in the morning”, said Dr. Clive Spray, CSO of Integrated Cannabis.

 

About Integrated Cannabis Company, Inc.

 

Integrated Cannabis Company, Inc. is comprised of dedicated scientists and product engineers who are passionate about health and creating health and lifestyle products utilizing advanced delivery systems and formulations. For more information, please visit the company’s website at: www.x-sprays.com.

 

ON BEHALF OF THE BOARD

“John Knapp”

Chief Executive Officer

For further information, please contact:

Telephone: 778-403-3358

Website: www.X-SPRAYS.com

 

The CSE does not accept responsibility for the adequacy or accuracy of this release. 

 

Neither the Canadian Securities Exchange nor its Market Regulator (as that term is defined in the policies of the Canadian Securities Exchange) accepts responsibility for the adequacy or accuracy of this release. The Canadian Securities Exchange has not in any way passed upon the merits of the proposed transaction and has neither approved nor disapproved the contents of this press release.

 

This news release may include forward-looking statements that are subject to risks and uncertainties. All statements within, other than statements of historical fact, are to be considered forward looking. Although the Company believes the expectations expressed in such forward-looking statements are based on reasonable assumptions, such statements are not guarantees of future performance and actual results or developments may differ materially from those in forward-looking statements. Factors that could cause actual results to differ materially from those in forward-looking statements include market prices, exploitation and exploration successes, continued availability of capital and financing, and general economic, market or business conditions. There can be no assurances that such statements will prove accurate and, therefore, readers are advised to rely on their own evaluation of such uncertainties. We do not assume any obligation to update any forward-looking statements except as required under the applicable laws.

Source:  Integrated Cannabis Company, Inc.

Integrated Cannabis Company, Inc. Signs Co-Development and Marketing Agreement with, a Canadian Licensed Producer, GTEC Holdings Ltd.

VANCOUVER, BRITISH COLUMBIA – September 27, 2018 – Integrated Cannabis Company, Inc. (CSE: ICAN, OTCQB: ICNAF) (“Integrated Cannabis”), is pleased to announce the completion of a Letter Agreement (the “Agreement”) to collaborate on X-SPRAYSTM products for the Canadian market with GTEC Holdings Ltd (“GTEC”) (TSXV: GTEC, OTCPK:GGTTF), a Canadian License Producer under Health Canada’s Access to Cannabis for Medical Purposes Regulations (ACMPR).

 

The Agreement allows for the co-development and marketing of novel spray products, utilizing proprietary nanotization technology containing both Cannabidiol (CBD) and/or Tetrahydrocannabinol (THC) for distribution in the Canadian medicinal and recreational markets. The Agreement is subject to the implementation of federal legislation in Canada and corresponding provincial and territorial legislation that permits the distribution and sale of certain formats of cannabis products, including without limitation sprays.

 

Over the coming weeks the companies will engage with their science, marketing and distribution teams to streamline the logistics of developing and ultimately introducing products to the Canadian marketplace.

 

“Partnering with a Canadian Licensed Producer has been a major goal of ours in order to facilitate the expansion of our product line into legal, established marketplaces.  The GTEC team is an ideal partner given their status as a LP and their tenure in the cannabis industry and provide a great alliance for our innovative product line,” said Mr. John Knapp, CEO of Integrated Cannabis.

 

“We are very excited to be working with Integrated Cannabis and their line of the X-SPRAYSTM products. As we continue to push towards positioning ourselves as a preeminent cannabis company it is critical to diversify our product offering with formulations that are both novel and offer alternative delivery methods,” said Mr. Norton Singhavon, CEO of GTEC.

 

The companies aim to have a definitive agreement in place by October 31, 2018.

 

About GTEC Holdings Ltd.

GTEC was founded in 2017 to capitalize on opportunities in the nascent and rapidly growing legal cannabis industry.  GTEC is focused on growing premium quality craft cannabis in purpose-built indoor facilities.  The Company also has a number of retail cannabis initiatives in Western Canada.  GTEC currently holds a 100% interest in GreenTec Bio-Pharmaceuticals Corp., Tumbleweed Farms Corp., Falcon Ridge Naturals Ltd., Alberta Craft Cannabis Inc., Grey Bruce Farms Inc., Zenalytic Laboratories Ltd. and Spectre Labs Inc. GTEC is a publicly-traded corporation based in Kelowna, British Columbia. The Company’s shares are listed on the TSX Venture Exchange and OTC Pink Sheets.

 

About Integrated Cannabis Company, Inc.

Integrated Cannabis Company, Inc. is comprised of dedicated scientists and product engineers who are passionate about health and creating health and lifestyle products utilizing advanced delivery systems and formulations. For more information, please visit the company’s website at: www.x-sprays.com.

 

ON BEHALF OF THE BOARD

“John Knapp”

Chief Executive Officer

For further information, please contact:

Telephone: 778-403-3358

Website: www.X-SPRAYS.com

 

The CSE does not accept responsibility for the adequacy or accuracy of this release. 

 

Neither the Canadian Securities Exchange nor its Market Regulator (as that term is defined in the policies of the Canadian Securities Exchange) accepts responsibility for the adequacy or accuracy of this release. The Canadian Securities Exchange has not in any way passed upon the merits of the proposed transaction and has neither approved nor disapproved the contents of this press release.

 

This news release may include forward-looking statements that are subject to risks and uncertainties. All statements within, other than statements of historical fact, are to be considered forward looking. Although the Company believes the expectations expressed in such forward-looking statements are based on reasonable assumptions, such statements are not guarantees of future performance and actual results or developments may differ materially from those in forward-looking statements. Factors that could cause actual results to differ materially from those in forward-looking statements include market prices, exploitation and exploration successes, continued availability of capital and financing, and general economic, market or business conditions. There can be no assurances that such statements will prove accurate and, therefore, readers are advised to rely on their own evaluation of such uncertainties. We do not assume any obligation to update any forward-looking statements except as required under the applicable laws.

 

Source:  Integrated Cannabis Company, Inc.

Integrated Cannabis Company, Inc. Signs Distribution Agreement with Empower Clinics, Inc.

VANCOUVER, British Columbia, September 20, 2018 /PRNewswire/ — Integrated Cannabis Company, Inc. (CSE: ICAN) (OTCQB: ICNAF) (“Integrated Cannabis”), is pleased to announce the completion of a Letter of Intent (LOI) to distribute X-SPRAYS™ products throughout the clinics and doctors’ offices of Empower Clinics Inc. (CSE: EPW) (FRA: 8EC) (“Empower”), a leading owner and operator of medical cannabis and wellness clinics in the United States (US).

 

The companies have recently engaged with their marketing and distribution teams to streamline the logistics of rolling out new products in the Empower clinics. Integrated Cannabis will distribute all of its CBD-infused X-SPRAYS™ including; CBD, Sleep, Recover, Libido and Energy throughout the Empower ecosystem.

 

“We believe this milestone marks another significant move for distribution of X-SPRAYS™ in key markets across the United States. In addition, we believe this alliance will help increase awareness from credible sources about alternative treatments for those struggling with opioid addiction, pain, anxiety, sleep issues and people seeking overall well-being,” said Mr. John Knapp, CEO of Integrated Cannabis. The Company expects to sign a definitive agreement with Empower in the coming weeks.

 

“We are very excited about our partnership with X-SPRAYS as we believe it brings leading technology and treatment for the most common conditions our patients face. X-SPRAYS state of the art product formulations and unique metered dosage help consistently deliver a world class product,” said Mr. Craig Snyder, CEO of Empower.

 

As of August 31, Empower has more than 25,000 patients under care across 15 locations with medical cannabis treatments in Oregon, Washington and Illinois. The patient base in Oregon represents approximately one-third of the state’s total medical card issuance. In addition, Empower has an historical patient database of more than 120,000 in the two states.

 

On September 12, Empower announced the opening of its flagship Chicago clinic. In Illinois, the company seeks to expand its operations and achieve a leadership position as it executes on parallel national clinic and product strategies. There is currently an opioid epidemic in the United States and the company’s announced Chicago facility closely followed the endorsement by Illinois Governor Bruce Rauner of medical cannabis as a frontline treatment and alternative for patients with a new statewide measure he signed into law on Aug 28.

 

ABOUT Empower

Empower is a leading owner and operator of medical cannabis and wellness clinics, as well as a developer of medical products in the US, focused on enabling individuals to improve and protect their health. The company provides treatment solutions through its physician-staffed clinics that are focused on education, data, and efficacy. Empower is a recognized leader and the first choice for patients seeking quality experience and improved health.

 

About Integrated Cannabis Company

Integrated Cannabis Company, Inc. is comprised of dedicated scientists and product engineers who are passionate about health and creating health and lifestyle products utilizing advanced delivery systems and formulations. For more information, please visit the company’s website at: http://www.x-sprays.com.

 

On Behalf Of The Board

‘John Knapp’
Chief Executive Officer

 

The CSE does not accept responsibility for the adequacy or accuracy of this release.

 

Neither the Canadian Securities Exchange nor its Market Regulator (as that term is defined in the policies of the Canadian Securities Exchange) accepts responsibility for the adequacy or accuracy of this release. The Canadian Securities Exchange has not in any way passed upon the merits of the proposed transaction and has neither approved nor disapproved the contents of this press release.

 

This news release may include forward-looking statements that are subject to risks and uncertainties. All statements within, other than statements of historical fact, are to be considered forward looking. Although the Company believes the expectations expressed in such forward-looking statements are based on reasonable assumptions, such statements are not guarantees of future performance and actual results or developments may differ materially from those in forward-looking statements. Factors that could cause actual results to differ materially from those in forward-looking statements include market prices, exploitation and exploration successes, continued availability of capital and financing, and general economic, market or business conditions. There can be no assurances that such statements will prove accurate and, therefore, readers are advised to rely on their own evaluation of such uncertainties. We do not assume any obligation to update any forward-looking statements except as required under the applicable laws.

 

For further information, please contact:
Telephone: +1-778-403-3358
Email: info@cnrpmining.com

 

SOURCE Integrated Cannabis Company, Inc.

Integrated Cannabis Company, Inc. Develops THC Infused Spray Product

VANCOUVER, British Columbia, Sept. 13, 2018 /PRNewswire/ — Integrated Cannabis Company, Inc. (CSE: ICAN) (OTCQB: ICNAF) (ICAN.CN) (the “Company” or “Integrated Cannabis”), is pleased to announce the completion of a market ready Tetrahydrocannabinol (THC)-infused spray product and the required licensure for manufacturing of the product in Colorado.

 

Over the past ten months the Company has engaged and worked with contractors, consultants and various state and municipal regulators in order to successfully gain licensing and approvals for facilities that manufacture CBD- and THC-infused products in the State of Colorado.

 

The THC product employs the same nanotechnology used to enhance the CBD-infused X-SPRAYS™, resulting in higher bioavailability and faster uptake versus capsules or powder.  The Company continues to enhance the flavor profiles in order to find an optimal formula.

 

“We are pleased to be adding THC products to our proprietary line of sprays and plan to launch via distribution in Colorado beginning in Q4 and shall pursue other legal markets thereafter,” said Mr. John Knapp, CEO of Integrated Cannabis.

 

To best demonstrate the Company’s activities in the Manufacturer of Infused Products (MIP) area, a chronological outline follows:

 

  • Completed the build out of a commercial kitchen adjacent to a licensed Medical and Recreational extraction lab
  • Completed Process Validation with the Colorado Marijuana Enforcement Division (MED)
  • Secured a high-quality CBD source from a supplier with Colorado Department of Public Health and Environment (CDPHE) Registration Certificate and Colorado Hemp License
  • Received Shelf Stability approval to sell X-SPRAYS™ CBD formulation in Denver
  • Received approval to sell CBD formulated products throughout all of Colorado
  • Secured a high-quality THC source from a duly licensed Colorado Medical and Recreational extraction lab
  • Received approval to sell THC formulated products throughout most of Colorado – only awaiting approval for City of Denver
  • Submitted Shelf Stability application to sell X-SPRAYS™ THC formulation in Denver

About Integrated Cannabis Company

Integrated Cannabis Company, Inc. is comprised of dedicated scientists and product engineers who are passionate about health and creating health and lifestyle products utilizing advanced delivery systems and formulations. For more information, please visit the company’s website at: www.x-sprays.com.

 

ON BEHALF OF THE BOARD

“John Knapp”
Chief Executive Officer

 

The CSE does not accept responsibility for the adequacy or accuracy of this release.

 

Neither the Canadian Securities Exchange nor its Market Regulator (as that term is defined in the policies of the Canadian Securities Exchange) accepts responsibility for the adequacy or accuracy of this release. The Canadian Securities Exchange has not in any way passed upon the merits of the proposed transaction and has neither approved nor disapproved the contents of this press release.

 

This news release may include forward-looking statements that are subject to risks and uncertainties. All statements within, other than statements of historical fact, are to be considered forward looking. Although the Company believes the expectations expressed in such forward-looking statements are based on reasonable assumptions, such statements are not guarantees of future performance and actual results or developments may differ materially from those in forward-looking statements. Factors that could cause actual results to differ materially from those in forward-looking statements include market prices, exploitation and exploration successes, continued availability of capital and financing, and general economic, market or business conditions. There can be no assurances that such statements will prove accurate and, therefore, readers are advised to rely on their own evaluation of such uncertainties. We do not assume any obligation to update any forward-looking statements except as required under the applicable laws.

 

For further information, please contact:

Eugene Beukman
Email: investors@cnrpmining.com

Jason Miller
+1-778-403-3358

 

SOURCE Integrated Cannabis Company, Inc.

Integrated Cannabis Company, Inc. Provides Corporate Update

VANCOUVER, British Columbia, Sept. 06, 2018 (GLOBE NEWSWIRE) — Integrated Cannabis Company, Inc. (CSE: ICAN, OTCQB: ICNAF) (the “Company” or “Integrated Cannabis”), is pleased to provide a corporate update.

 

Commercial Stage Products: X-SPRAYS
The Company’s X-SPRAYS™ product line consists of eight market ready orally ingested spray products that are highly effective for overall health and well-being as well as general lifestyle.  Four products are available infused with hemp-based cannabidiol (CBD) and four products are formulated without a cannabidiol (CBD) infusion.  The state of the art formulations are free from artificial flavours, artificial colours, sugar, starch, wheat, soy, gluten, eggs, salt and dairy.  The sprays contain natural fruit and/or herbal flavours and are suitable for vegetarians and vegans.  The products are highly bioavailable such that the active ingredients in the sprays are already fully dissolved, so the vitamins and minerals do not need to be further broken down once swallowed, but are immediately available for use by the body.

 

The X-SPRAYS™ product line is packaged in precise, metered dose and convenient spray tubes including a child-resistant version, both of which easily fit into a purse or pocket and are ideal for travel.  The container protects the liquid from light and air, ensuring the quality and shelf life of the ingredients.

 

The full product offering is listed below in Table 1.0.

Product Name Product Description / Use
CBD Stress relief, pain management
Sleep with CBD Sleep aid, non habit forming
Focus Mental clarity
Relief General relief
Sleep Sleep aid, non habit forming
Recover Anti-hangover
Energy Energy boost
Libido Aphrodisiac, enhance sexual vitality

 

X-SPRAYS Test MarketingOnline sales of the X-SPRAYS™ were initiated in late 2017 and have continued up to the present.  These sales have been encouraging, considering the previously limited marketing budget, and the Company has seen numerous repeat customer orders which demonstrates product uptake and consumer affinity for the X-SPRAYS™.

 

In addition to Internet sales, the Company has test marketed selected products in two Medical Marijuana dispensaries in Colorado.  These sales began in February 2018 and continue.  Proceeds from these sales have been reinvested in Colorado marketing initiatives. The Company has learned, however, that marketing combined with in-store promotions can generate minimum sales in excess of 1 product per day in the retail environment. While this number is insignificant from a revenue perspective on a small scale retail distribution, it becomes significant when considering retail distribution outlets in the hundreds of locations. A single product selling only one unit per day in 100 stores could generate wholesale revenue in excess of tens of thousands of dollars per day.  The Company has four products that are CBD infused, four non-CBD infused and a soon to be launched line of THC products that will have multiple SKU’s.  With market testing complete, X-SPRAYS™ plans to roll out additional brick and mortar distribution throughout dispensaries, vape stores, gas stations, and convenience stores across the country.

 

Additionally, the Company intends to launch an aggressive online marketing campaign to drive sales through the utilization of traditional on-line channels and via established product influencers.

 

Acquisition Opportunities
“We are currently in the late stages of reviewing a short list of potential acquisition opportunities that would broaden our product offering from the existing X-SPRAYS™ line to potentially licensed Cannabis formulations in several US States,” said Mr. John Knapp, CEO of Integrated Cannabis Company.  The Company will provide additional updates as required.

 

About Integrated Cannabis Company
Integrated Cannabis Company, Inc. is comprised of dedicated scientists and product engineers who are passionate about health and creating health and lifestyle products utilizing advanced delivery systems and formulations. For more information, please visit the company’s website at: www.x-sprays.com.

 

ON BEHALF OF THE BOARD

“John Knapp”
Chief Executive Officer

For further information, please contact: 
Eugene Beukman
Email: info@cnrpmining.com

 

The CSE does not accept responsibility for the adequacy or accuracy of this release.

 

Neither the Canadian Securities Exchange nor its Market Regulator (as that term is defined in the policies of the Canadian Securities Exchange) accepts responsibility for the adequacy or accuracy of this release. The Canadian Securities Exchange has not in any way passed upon the merits of the proposed transaction and has neither approved nor disapproved the contents of this press release.

 

This news release may include forward-looking statements that are subject to risks and uncertainties. All statements within, other than statements of historical fact, are to be considered forward looking. Although the Company believes the expectations expressed in such forward-looking statements are based on reasonable assumptions, such statements are not guarantees of future performance and actual results or developments may differ materially from those in forward-looking statements. Factors that could cause actual results to differ materially from those in forward-looking statements include market prices, exploitation and exploration successes, continued availability of capital and financing, and general economic, market or business conditions. There can be no assurances that such statements will prove accurate and, therefore, readers are advised to rely on their own evaluation of such uncertainties. We do not assume any obligation to update any forward-looking statements except as required under the applicable laws.

 

Source: Integrated Cannabis Company Inc.

About Integrated Cannabis Company

(CSE:ICAN.CN) (OTCQB:ICNAF)

 

NO PILLS. NO POWDERS. JUST SPRAY.

 

All Natural Ingredients | Fast Acting & Effective | American-made Quality

 

Our founder, Dr. Clive Spray PhD, has dedicated his life to improving the quality of other people’s health.

Over the last 20 years, the chemist and plant biologist has been committed to finding natural solutions to life’s lingering problems. Combining an understanding of both traditional ethno-botany with the cutting edge of nutritional science, Dr. Spray has created several formulations designed to help in the areas where we need it most, whether it is helping insomnia, increasing libido, or alleviating pain.

 

As nationwide attitudes surrounding cannabis and cannabinoids have changed, we have taken this opportunity to work on formulations containing CBD, an incredibly therapeutic and non-psychoactive cannabinoid. Our work with CBD has opened up an entirely new realm for our formulations and allowed us to provide even more relief to our consumers. As a result, we are now able to offer almost all of our formulations in both a CBD and non-CBD version.

 

Formulations, however, are only one piece of the puzzle. You can have the best supplement in the world, yet without an effective way to deliver it, it is worthless. Dr. Spray’s quest to find the most effective way for the body to process his formulations coincidentally led him back to his name sake, the spray. As you can read more about here, sublingual sprays offer an unparalleled bioavailability that lets our supplements start working for you as soon as you Spray.

 

The team at X-SPRAYS™, led by Dr. Spray, have worked tirelessly to bring you this line of products.

 

We hope to have the opportunity to share the power of sprays.

 

The Science


Numerous studies have shown that oral spray delivery systems, such as those used in X-SPRAYS™ products, serve as more effective delivery systems than pills, capsules, or even sublingual tablets.  Here are a few such studies.

 

International Journal of Pharmacy & Life Sciences: Intra Oral Sprays- An Overview

Over the last three decades, intraoral dosage forms have been evolving as an acceptable and in some cases as the preferred, alternative to conventional tablets and capsules. Among them, Oral sprays are the fastest, most effective and comfortable way to take medicines, nutrients, minerals and vitamins. They have been acquiring important position in the market by overcoming previously encountered administration problems and contributing to extension of patent life. Oral sprays have the unique property of rapidly releasing the drug in the oral cavity, thus obviating the requirement of water during administration. Therefore, these dosage forms have lured the market for a certain section of the patient population which includes dysphagic, bed ridden, and psychic, geriatric patients. This article focuses on the transmucosal view , spray formulation aspects , advances made so far in the field oral sprays and patented technologies.

 

A Multi Center TrialStudies on the response of nitroglycerin oral spray compared with sublingual tablets for angina pectoris patients with dry mouth.
1997
Feb;47(2):128-31.

Authors:  Sato, H; Koretsune, Y; Taniguchi, T; Fukui, S; Shimazu, T; Sugii, M; Matsuyama, T; Karita, M; Hori, M.

Abstract: Nitroglycerin (glyceryl trinitrate, CAS 55-63-0, NTG) administered with an oral spray may be more effective in relieving anginal pain than sublingual tablets especially when the patient’s mouth is dry. In this study, the effect of a NTG oral spray (Myocor Spray) on exercise-induced angina was compared with that of a sublingual tablet in relation to the oral dryness. In 17 patients with effort angina, graded bicycle exercise was performed twice at an interval of one week. Exercise was discontinued upon the onset of moderate anginal pain. Immediately after exercise, the oral dryness was evaluated by touching the tip of the tongue with a blotting paper for a moment. Then, 0.3 mg of NTG was administered by either a squirt of spray or a sublingual tablet in a randomized crossover fashion. Exercise results were reproducible between two exercise tests. According to the extent of the wet area of the blotting paper, the subjects were divided into two groups. In 7 patients of the wet group, the remission times of chest pain and ST segment depression were not significantly different by the formulation of NTG. In 10 patients of the dry group, however, both chest pain and ST depression more rapidly recovered with use of the oral spray (p < 0.05 and p < 0.05, respectively). These results strongly suggest that the NTG oral spray is superior to the sublingual tablet in relieving anginal attacks, when the oral wetness is decreased.

 

A Symposium: Advances in Clinical Practice of Nitrate Therapy – More rapid relief of pain with isosorbide dinitrate oral spray than with sublingual tablets in elderly patients with angina pectoris
The American Journal of CariologyVolume: 61 (1988)Authors: Reisin, LH; Landau, E; Darawshi, A.Abstract: To evaluate the possibility of improving clinical practice in the treatment of angina pectoris, the duration of relief of pain with isosorbide dinitrate (ISDN) oral spray and sublingual tablets were compared in elderly patients with chronic stable angina pectoris. Nine patients (mean age 67 years) were studied in a randomized crossover trial. The patients underwent bicycle ergometry, which resulted in typical chest pain associated with electrocardiographic ST-segment depression in all 9. The patients received ISDN oral spray or sublingual tablets immediately on termination of exercise. At least 6 hours later another ergometry test was performed and the patients were crossed over to the other drug. ISDN spray relieved pain in all patients at a mean duration of 61.6 +/- 24.4 seconds after administration, whereas the duration of relief of pain by ISDN sublingual tablets was 112.4 +/- 70 seconds. The difference was highly significant (p < 0.0005). It is concluded that clinical practice of treatment of angina pectoris in the elderly can be improved by using ISDN oral spray rather than sublingual tablets. The spray is effective at twice the rapidity of the sublingual tablet.

 

Source:  https://www.x-sprays.com/

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